Laboratory biochemistry: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Laboratory biochemistry

Sample item

What does glycated haemoglobin primarily reflect?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Average glucose exposure over roughly three months

HbA1c reflects cumulative glucose exposure over the lifespan of circulating red cells and is used to assess longer-term glycaemic control.

Option by option

  • A. Glucose level during the last five minutes

    A finger-prick glucose gives immediate concentration.

  • B. Average glucose exposure over roughly three months (correct)

    Correct: HbA1c estimates longer-term average glycaemia.

  • C. Insulin secretion after one meal

    Meal insulin response needs other testing.

  • D. Renal filtration rate

    Renal filtration is estimated by creatinine-based measures.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is B, Average glucose exposure over roughly three months. HbA1c reflects cumulative glucose exposure over the lifespan of circulating red cells and is used to assess longer-term glycaemic control.

Why is "Glucose level during the last five minutes" not the answer?

A finger-prick glucose gives immediate concentration.

Why is "Insulin secretion after one meal" not the answer?

Meal insulin response needs other testing.

Why is "Renal filtration rate" not the answer?

Renal filtration is estimated by creatinine-based measures.

What concept does this question test?

It tests Laboratory biochemistry in Biochemistry. The correct option holds because: Correct: HbA1c estimates longer-term average glycaemia.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Laboratory biochemistry?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.