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Pathology · Inflammation
Sample itemWhich chemokine is a major signal recruiting neutrophils to acute inflammatory sites?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Interleukin-8
Interleukin-8 is a potent neutrophil chemokine that directs these cells from the bloodstream toward sites of acute tissue injury or infection.
Option by option
A. Thyroxine
Thyroxine regulates metabolic rate and development.
B. Erythropoietin
Erythropoietin stimulates erythroid precursor production in marrow.
C. Interleukin-4
IL-4 promotes type 2 immune responses rather than neutrophil chemotaxis.
D. Interleukin-8 (correct)
Correct: IL-8 provides chemotactic recruitment for neutrophils.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.