Substance use: opioid intoxication: practice question

A Psychiatry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Psychiatry · Substance use: opioid intoxication

Sample item

A drowsy patient has pinpoint pupils, a respiratory rate of 6/min, and oxygen desaturation after taking an unknown tablet. Which immediate antidote is most appropriate while supporting ventilation?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Naloxone

The opioid toxidrome includes CNS depression, respiratory depression, and miosis. Naloxone reverses opioid receptor effects, but airway and ventilatory support remain urgent priorities.

Option by option

  • A. Thiamine

    Thiamine is important in alcohol-related nutritional deficiency, not an opioid antidote.

  • B. Flumazenil

    Flumazenil reverses benzodiazepines and may precipitate seizures in some patients.

  • C. Dantrolene

    Dantrolene treats malignant hyperthermia.

  • D. Naloxone (correct)

    Correct. Naloxone is the opioid antagonist used for suspected opioid-induced respiratory depression.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Psychiatry questions

Questions about this Psychiatry question

What is the answer to this Psychiatry question?

The best answer is D, Naloxone. The opioid toxidrome includes CNS depression, respiratory depression, and miosis.

Why is "Thiamine" not the answer?

Thiamine is important in alcohol-related nutritional deficiency, not an opioid antidote.

Why is "Flumazenil" not the answer?

Flumazenil reverses benzodiazepines and may precipitate seizures in some patients.

Why is "Dantrolene" not the answer?

Dantrolene treats malignant hyperthermia.

What concept does this question test?

It tests Substance use: opioid intoxication in Psychiatry. Naloxone reverses opioid receptor effects, but airway and ventilatory support remain urgent priorities.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Substance use: opioid intoxication?

Learn each diagnosis by its core features and its first-line treatment. Then use the flashcards and the other Psychiatry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.