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Psychiatry · Sleep-wake disorders: narcolepsy
Sample itemA student has irresistible daytime sleep episodes and suddenly loses muscle tone when laughing, while remaining conscious. Which diagnosis is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Narcolepsy with cataplexy
Narcolepsy is characterized by excessive daytime sleepiness; cataplexy is sudden emotion-triggered loss of muscle tone with preserved consciousness. Other REM-related phenomena may also occur.
Option by option
A. Obstructive sleep apnea
Obstructive sleep apnea causes sleep fragmentation and daytime sleepiness but not cataplexy.
B. Nightmare disorder
Nightmare disorder causes dysphoric dreams, not daytime sleep attacks.
C. REM sleep behavior disorder
REM sleep behavior disorder involves acting out dreams because of loss of REM atonia.
D. Narcolepsy with cataplexy (correct)
Correct. Laughter-triggered loss of tone is cataplexy, strongly suggesting narcolepsy type 1.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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