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OBG · Gynecology: polycystic ovary syndrome
Sample itemA patient has irregular menses, clinical hyperandrogenism, and polycystic ovarian morphology after other causes are excluded. Which diagnosis fits best?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Polycystic ovary syndrome
Polycystic ovary syndrome is diagnosed using a combination of ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology after exclusion of alternative causes. Metabolic and endometrial risks also need assessment.
Option by option
A. Primary ovarian insufficiency
Primary ovarian insufficiency is associated with elevated gonadotropins and low estrogen.
B. Polycystic ovary syndrome (correct)
Correct. This is the characteristic diagnostic combination.
C. Endometrial cancer
Endometrial cancer is not the primary explanation for this endocrine phenotype.
D. Hyperprolactinemia only
Hyperprolactinemia is an alternative cause of menstrual irregularity that must be excluded.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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