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Pediatrics · Cardiology: duct-dependent lesions
Sample itemA newborn with critical coarctation becomes shocked and acidotic after the ductus arteriosus closes. Which infusion can maintain ductal patency while definitive care is arranged?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Prostaglandin E1
Prostaglandin E1 keeps the ductus arteriosus open in duct-dependent congenital heart disease and can restore systemic or pulmonary blood flow. It requires monitored use because apnea is a recognized adverse effect.
Option by option
A. Digoxin
Digoxin does not reopen the ductus.
B. Prostaglandin E1 (correct)
Correct. Prostaglandin E1 maintains ductal flow.
C. Indomethacin
Indomethacin promotes ductal closure.
D. Furosemide
Furosemide treats fluid overload, not ductal patency.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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