Autonomic drugs: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Autonomic drugs

Sample item

Which receptor blockade causes atropine-induced tachycardia?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Muscarinic M2 receptor blockade

Atropine blocks vagal muscarinic M2 receptors at the sinoatrial node, removing parasympathetic slowing and increasing heart rate.

Option by option

  • A. Beta-1 receptor blockade

    Beta-1 blockade generally slows heart rate.

  • B. Alpha-1 receptor blockade

    Alpha-1 blockade lowers vascular tone.

  • C. Nicotinic receptor blockade

    Nicotinic blockade is not the usual atropine mechanism.

  • D. Muscarinic M2 receptor blockade (correct)

    Correct: M2 blockade reduces vagal cardiac restraint.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is D, Muscarinic M2 receptor blockade. Atropine blocks vagal muscarinic M2 receptors at the sinoatrial node, removing parasympathetic slowing and increasing heart rate.

Why is "Beta-1 receptor blockade" not the answer?

Beta-1 blockade generally slows heart rate.

Why is "Alpha-1 receptor blockade" not the answer?

Alpha-1 blockade lowers vascular tone.

Why is "Nicotinic receptor blockade" not the answer?

Nicotinic blockade is not the usual atropine mechanism.

What concept does this question test?

It tests Autonomic drugs in Pharmacology. The correct option holds because: Correct: M2 blockade reduces vagal cardiac restraint.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Autonomic drugs?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.