Adverse effects: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Adverse effects

Sample item

Which reaction is most consistent with a type B adverse drug reaction?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Agranulocytosis from an idiosyncratic drug response

Type B adverse reactions are unpredictable and not dose-related, often reflecting idiosyncratic or immune mechanisms such as drug-induced agranulocytosis.

Option by option

  • A. Sedation after high opioid dose

    Opioid sedation is dose-related.

  • B. Agranulocytosis from an idiosyncratic drug response (correct)

    Correct: idiosyncratic agranulocytosis is unpredictable.

  • C. Hypotension from excessive antihypertensive dose

    Excess antihypertensive effect is dose-related type A.

  • D. Bleeding from excess anticoagulation

    Anticoagulant bleeding is predictable pharmacology.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is B, Agranulocytosis from an idiosyncratic drug response. Type B adverse reactions are unpredictable and not dose-related, often reflecting idiosyncratic or immune mechanisms such as drug-induced agranulocytosis.

Why is "Sedation after high opioid dose" not the answer?

Opioid sedation is dose-related.

Why is "Hypotension from excessive antihypertensive dose" not the answer?

Excess antihypertensive effect is dose-related type A.

Why is "Bleeding from excess anticoagulation" not the answer?

Anticoagulant bleeding is predictable pharmacology.

What concept does this question test?

It tests Adverse effects in Pharmacology. The correct option holds because: Correct: idiosyncratic agranulocytosis is unpredictable.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Adverse effects?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.