Nephrology: acute kidney injury: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Nephrology: acute kidney injury

Sample item

Which urine finding most strongly supports acute tubular necrosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Muddy brown granular casts

Pigmented granular casts formed from injured tubular cells are characteristic of acute tubular necrosis. Red-cell casts suggest glomerulonephritis.

Option by option

  • A. Oval fat bodies

    Oval fat bodies occur in nephrotic syndrome.

  • B. Eosinophils only

    Eosinophils may occur in interstitial nephritis.

  • C. Red-cell casts

    Red-cell casts point to glomerular bleeding.

  • D. Muddy brown granular casts (correct)

    Correct. Muddy brown casts are a classic ATN clue.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is D, Muddy brown granular casts. Pigmented granular casts formed from injured tubular cells are characteristic of acute tubular necrosis.

Why is "Oval fat bodies" not the answer?

Oval fat bodies occur in nephrotic syndrome.

Why is "Eosinophils only" not the answer?

Eosinophils may occur in interstitial nephritis.

Why is "Red-cell casts" not the answer?

Red-cell casts point to glomerular bleeding.

What concept does this question test?

It tests Nephrology: acute kidney injury in General Medicine. Red-cell casts suggest glomerulonephritis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nephrology: acute kidney injury?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.