Neurology: myasthenia gravis: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Neurology: myasthenia gravis

Sample item

Ptosis that worsens through the day and improves with rest is most consistent with what disorder?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Myasthenia gravis

Myasthenia gravis is antibody-mediated postsynaptic neuromuscular-junction disease producing fatigable ocular and bulbar weakness.

Option by option

  • A. Botulism

    Botulism often causes acute descending paralysis with autonomic signs.

  • B. Parkinson disease

    Parkinson disease causes bradykinesia and rigidity.

  • C. Lambert-Eaton syndrome

    Lambert-Eaton often improves with repeated use and has autonomic symptoms.

  • D. Myasthenia gravis (correct)

    Correct. Fluctuating fatigability is characteristic.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is D, Myasthenia gravis. Myasthenia gravis is antibody-mediated postsynaptic neuromuscular-junction disease producing fatigable ocular and bulbar weakness.

Why is "Botulism" not the answer?

Botulism often causes acute descending paralysis with autonomic signs.

Why is "Parkinson disease" not the answer?

Parkinson disease causes bradykinesia and rigidity.

Why is "Lambert-Eaton syndrome" not the answer?

Lambert-Eaton often improves with repeated use and has autonomic symptoms.

What concept does this question test?

It tests Neurology: myasthenia gravis in General Medicine. The correct option holds because: Correct. Fluctuating fatigability is characteristic.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neurology: myasthenia gravis?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.