Acid-base: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Acid-base

Sample item

What is the main renal response to chronic respiratory acidosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Increase bicarbonate reabsorption and hydrogen excretion

In chronic respiratory acidosis, kidneys compensate by increasing bicarbonate retention and acid excretion, partially restoring plasma pH.

Option by option

  • A. Reduce all sodium reabsorption

    Sodium handling is not stopped globally.

  • B. Increase bicarbonate reabsorption and hydrogen excretion (correct)

    Correct: renal bicarbonate retention compensates respiratory CO2 retention.

  • C. Excrete more bicarbonate immediately

    Bicarbonate excretion would worsen acidosis.

  • D. Stop ammonium production

    Ammonium excretion helps remove acid.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is B, Increase bicarbonate reabsorption and hydrogen excretion. In chronic respiratory acidosis, kidneys compensate by increasing bicarbonate retention and acid excretion, partially restoring plasma pH.

Why is "Reduce all sodium reabsorption" not the answer?

Sodium handling is not stopped globally.

Why is "Excrete more bicarbonate immediately" not the answer?

Bicarbonate excretion would worsen acidosis.

Why is "Stop ammonium production" not the answer?

Ammonium excretion helps remove acid.

What concept does this question test?

It tests Acid-base in Biochemistry. The correct option holds because: Correct: renal bicarbonate retention compensates respiratory CO2 retention.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Acid-base?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.