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Pathology · Wound healing
Sample itemWhat is wound contraction primarily mediated by?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Myofibroblasts
Myofibroblasts contain contractile elements and draw wound edges together during healing, reducing the size of granulating tissue.
Option by option
A. Mast cells
Mast cells release inflammatory mediators.
B. Myofibroblasts (correct)
Correct: myofibroblasts contract healing wounds.
C. Neutrophils
Neutrophils provide acute antimicrobial defence.
D. Osteoclasts
Osteoclasts resorb bone.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.