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General Surgery · Urology: renal cell carcinoma
Sample itemA patient has intermittent painless hematuria, flank mass, weight loss, and varicocele that does not decompress when supine. What diagnosis is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Renal cell carcinoma
Renal cell carcinoma can cause hematuria, flank mass, constitutional symptoms, and a persistent varicocele from renal-vein involvement. Imaging and urologic assessment are required.
Option by option
A. Ureteric stone only
Stones cause colic and hematuria but not a mass or venous obstruction pattern.
B. Uncomplicated cystitis
Cystitis causes dysuria and frequency, not flank mass and persistent varicocele.
C. Benign prostatic hyperplasia
BPH causes lower urinary tract symptoms, not flank mass.
D. Renal cell carcinoma (correct)
Correct. This combination is a classic renal-cell-carcinoma presentation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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