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Pediatrics · Gastroenterology: biliary atresia
Sample itemA 5-week-old has persistent jaundice, pale stools, dark urine, hepatomegaly, and elevated conjugated bilirubin. What diagnosis requires urgent referral?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Biliary atresia
Biliary atresia causes obstructive conjugated jaundice, acholic stools, and progressive liver damage in infancy. Early specialist intervention offers the best chance of preserving bile flow.
Option by option
A. Physiologic neonatal jaundice
Physiologic jaundice is unconjugated and resolves earlier.
B. Breast-milk jaundice only
Breast-milk jaundice does not cause pale stools or conjugated hyperbilirubinemia.
C. Biliary atresia (correct)
Correct. Pale stools with conjugated jaundice are a major red flag.
D. Gilbert syndrome
Gilbert syndrome is mild unconjugated hyperbilirubinemia in older children or adults.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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