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Pharmacology · Psychiatric drugs
Sample itemWhy must lithium concentration be monitored?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Narrow therapeutic range and renal clearance
Lithium is cleared by kidneys and has a narrow range between efficacy and toxicity; dehydration and interacting drugs can raise concentrations.
Option by option
A. Narrow therapeutic range and renal clearance (correct)
Correct: renal handling and narrow range require monitoring.
B. It has no drug interactions
Many interactions affect lithium levels.
C. It permanently binds platelets
Platelet binding is not its key property.
D. It is absorbed only through skin
Lithium is administered systemically, not only through skin.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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