Gastrointestinal drugs: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Gastrointestinal drugs

Sample item

Why is long-term proton-pump inhibitor therapy reviewed regularly?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Potential adverse effects and ongoing indication need reassessment

Long-term PPI therapy should be periodically reviewed because of possible adverse effects, interactions, and the need to use the lowest effective duration.

Option by option

  • A. It permanently sterilizes the bowel

    PPIs do not sterilize bowel permanently.

  • B. Potential adverse effects and ongoing indication need reassessment (correct)

    Correct: indication and risk should be reassessed.

  • C. It reverses all reflux anatomy

    They do not correct structural reflux causes.

  • D. It always causes immediate liver failure

    Liver failure is not inevitable.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is B, Potential adverse effects and ongoing indication need reassessment. Long-term PPI therapy should be periodically reviewed because of possible adverse effects, interactions, and the need to use the lowest effective duration.

Why is "It permanently sterilizes the bowel" not the answer?

PPIs do not sterilize bowel permanently.

Why is "It reverses all reflux anatomy" not the answer?

They do not correct structural reflux causes.

Why is "It always causes immediate liver failure" not the answer?

Liver failure is not inevitable.

What concept does this question test?

It tests Gastrointestinal drugs in Pharmacology. The correct option holds because: Correct: indication and risk should be reassessed.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal drugs?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.