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Psychiatry · Psychopharmacology
Sample itemWhat adverse effect requires urgent review in a patient taking clozapine?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Fever and sore throat suggesting neutropenia
Clozapine can cause agranulocytosis, so fever or sore throat requires urgent blood count assessment and drug-safety review.
Option by option
A. Mild dry mouth only
Dry mouth is less immediately dangerous.
B. Stable corrective-lens prescription
Lens prescription is unrelated.
C. Fever and sore throat suggesting neutropenia (correct)
Correct: infection symptoms may signal dangerous neutropenia.
D. Transient hunger after meals
Hunger is nonspecific.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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