Antenatal medicine: anticoagulation: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Antenatal medicine: anticoagulation

Sample item

Why is low-molecular-weight heparin commonly preferred over warfarin for anticoagulation during pregnancy?

AIt does not cross the placentaBIt eliminates all thrombosis riskCIt causes fetal vitamin K excessDIt permanently prevents postpartum bleeding

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. It does not cross the placenta

Heparins do not cross the placenta and are used for many pregnancy anticoagulation indications. Warfarin crosses the placenta and can cause fetal complications, especially during organogenesis.

Option by option

A. It does not cross the placenta (correct)
Correct. Lack of placental transfer is the key fetal safety advantage.
B. It eliminates all thrombosis risk
No treatment eliminates all thrombotic risk.
C. It causes fetal vitamin K excess
Vitamin K excess is not the relevant mechanism.
D. It permanently prevents postpartum bleeding
Anticoagulation can increase bleeding risk and does not permanently prevent it.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, It does not cross the placenta. Heparins do not cross the placenta and are used for many pregnancy anticoagulation indications.

Why is "It eliminates all thrombosis risk" not the answer?

No treatment eliminates all thrombotic risk.

Why is "It causes fetal vitamin K excess" not the answer?

Vitamin K excess is not the relevant mechanism.

Why is "It permanently prevents postpartum bleeding" not the answer?

Anticoagulation can increase bleeding risk and does not permanently prevent it.

What concept does this question test?

It tests Antenatal medicine: anticoagulation in OBG. Warfarin crosses the placenta and can cause fetal complications, especially during organogenesis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antenatal medicine: anticoagulation?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.