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Pediatrics · Nutrition: iron deficiency
Sample itemWhich laboratory profile is most typical of iron-deficiency anemia in a child?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Low ferritin with high total iron-binding capacity
Iron deficiency lowers body iron stores and ferritin while increasing total iron-binding capacity. Inflammation can elevate ferritin, so the clinical context matters.
Option by option
A. High MCV with high B12 level
High MCV suggests macrocytosis rather than iron deficiency.
B. High ferritin with low total iron-binding capacity
High ferritin with low TIBC favors anemia of inflammation.
C. Reticulocytosis with high bilirubin
Reticulocytosis and bilirubin elevation suggest hemolysis.
D. Low ferritin with high total iron-binding capacity (correct)
Correct. Low ferritin and high TIBC are classic iron-deficiency findings.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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