Antituberculous drugs: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antituberculous drugs

Sample item

Why is pyridoxine given with isoniazid in selected patients?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Prevent peripheral neuropathy

Isoniazid can deplete pyridoxine and cause peripheral neuropathy, particularly in malnutrition, diabetes, pregnancy, or alcohol dependence.

Option by option

  • A. Prevent peripheral neuropathy (correct)

    Correct: B6 prevents isoniazid-related neuropathy.

  • B. Treat hyperuricaemia

    Hyperuricaemia relates to pyrazinamide.

  • C. Reverse liver fibrosis

    Pyridoxine does not reverse fibrosis.

  • D. Prevent optic neuritis

    Optic toxicity is ethambutol concern.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Prevent peripheral neuropathy. Isoniazid can deplete pyridoxine and cause peripheral neuropathy, particularly in malnutrition, diabetes, pregnancy, or alcohol dependence.

Why is "Treat hyperuricaemia" not the answer?

Hyperuricaemia relates to pyrazinamide.

Why is "Reverse liver fibrosis" not the answer?

Pyridoxine does not reverse fibrosis.

Why is "Prevent optic neuritis" not the answer?

Optic toxicity is ethambutol concern.

What concept does this question test?

It tests Antituberculous drugs in Pharmacology. The correct option holds because: Correct: B6 prevents isoniazid-related neuropathy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antituberculous drugs?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.