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ENT · Rhinology
Sample itemA 22-year-old has recurrent sneezing, watery rhinorrhoea, nasal itching and pale boggy turbinates for six months, with no relief from antihistamines alone. Which drug class is the most effective single agent for the persistent symptoms?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Intranasal corticosteroids
Intranasal corticosteroids are the most effective single drug class for allergic rhinitis, relieving sneezing, itching, discharge and obstruction. Topical decongestants should be limited to a few days because of rhinitis medicamentosa.
Option by option
A. Intranasal corticosteroids (correct)
Correct. They suppress the allergic inflammatory response in the nasal mucosa.
B. Intranasal ipratropium bromide
Ipratropium helps rhinorrhoea but not sneezing or obstruction.
C. Oral leukotriene receptor antagonists
Leukotriene antagonists are less effective than nasal steroids and are an add-on option.
D. Topical nasal decongestants
Decongestants relieve obstruction only, and prolonged use causes rebound congestion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.