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Psychiatry · Catatonia
Sample itemA 25-year-old woman is mute, holds an odd posture for hours and resists passive movement, with waxy flexibility. She has refused food for two days. What is the most appropriate initial treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Intravenous or intramuscular lorazepam
Catatonia responds rapidly to benzodiazepines, and a lorazepam challenge is both diagnostic and therapeutic. ECT is used if there is no response or the course is malignant. Antipsychotics can worsen catatonia and precipitate neuroleptic malignant syndrome.
Option by option
A. Intravenous or intramuscular lorazepam (correct)
Correct. Benzodiazepines such as lorazepam are first-line for catatonia.
B. Oral imipramine
Tricyclic antidepressants do not treat catatonia and add anticholinergic and cardiac risks.
C. Oral lithium carbonate
Lithium has no role in the acute management of catatonia.
D. High-dose haloperidol injection
Antipsychotics may worsen catatonia and carry a risk of neuroleptic malignant syndrome.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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