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Radiology · Gastrointestinal imaging
Sample itemA young man has chronic diarrhoea and right iliac fossa pain. A barium follow-through shows a long, narrow, rigid terminal ileum, described as a 'string sign'. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Crohn disease
The string sign of Kantor represents persistent luminal narrowing from spasm and fibrosis in the terminal ileum of Crohn disease. Other signs include cobblestoning, skip lesions and fistulae. Ulcerative colitis is confined to the colon, apart from backwash ileitis.
Option by option
A. Ulcerative colitis
Ulcerative colitis involves the rectum and colon continuously and spares the small bowel.
B. Crohn disease (correct)
Correct. A narrowed rigid terminal ileum is the string sign of Crohn disease.
C. Carcinoid tumour
A carcinoid tumour causes a mesenteric mass with kinking rather than a long narrowed segment.
D. Intestinal lymphangiectasia
Lymphangiectasia gives a thickened fold pattern without strictures.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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