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ENT · Otology: glomus tumour
Sample itemA 50-year-old woman has pulsatile tinnitus that stops on compression of the ipsilateral carotid, and conductive hearing loss. Otoscopy shows a red, vascular mass behind an intact tympanic membrane that blanches on pneumatic pressure. What is the diagnosis, and why should a biopsy through the drum be avoided?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Glomus tympanicum (paraganglioma), because the lesion is highly vascular and may bleed profusely
Glomus tumours are paragangliomas that arise from glomus bodies in the middle ear (tympanicum) or at the jugular bulb (jugulare). They cause pulsatile tinnitus and conductive loss, and appear as a red 'rising sun' mass behind the drum that blanches on positive pressure (Brown sign). They are highly vascular, so biopsy risks severe haemorrhage. Diagnosis is by CT and MRI with angiography, and treatment is surgery or radiotherapy, and catecholamine secretion is excluded.
Option by option
A. Glomus tympanicum (paraganglioma), because the lesion is highly vascular and may bleed profusely (correct)
Correct. A pulsatile vascular mass behind the drum is a glomus tumour, and biopsy risks brisk bleeding.
B. Otosclerosis, because it may cause facial palsy
Otosclerosis may give a pink 'Schwartze sign' through the drum, but not a pulsatile vascular mass.
C. Acoustic neuroma, because it may seed the cerebrospinal fluid
Acoustic neuroma causes sensorineural loss and is not visible on otoscopy.
D. Cholesteatoma, because it may spread
Cholesteatoma appears as a white keratin mass in a retraction pocket and is not pulsatile.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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