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OBG · Early pregnancy: ectopic pregnancy
Sample itemA haemodynamically stable woman at 6 weeks has a 2.5 cm unruptured tubal ectopic pregnancy without fetal cardiac activity. Her serum beta-hCG is 2,500 IU/L. She is reliable for follow-up. What is the most appropriate management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Intramuscular methotrexate with weekly beta-hCG follow-up
Medical management with methotrexate (folate antagonist) is suitable for stable women with an unruptured ectopic, low and preferably falling hCG (below about 5,000 IU/L), a small mass (under 3.5 to 4 cm), no cardiac activity and reliable follow-up. Surgery is needed for instability, rupture, high hCG, or a fetal heartbeat. Folic acid-containing supplements should be avoided during treatment.
Option by option
A. Dilatation and curettage
Curettage removes intrauterine tissue and does not treat a tubal pregnancy.
B. Immediate laparotomy with salpingectomy
Laparotomy is for rupture or instability.
C. Expectant management without follow-up
Expectant management requires very low and falling hCG, with close follow-up.
D. Intramuscular methotrexate with weekly beta-hCG follow-up (correct)
Correct. She meets the criteria for medical treatment with methotrexate.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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