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OBG · Antenatal care: preterm prelabour rupture of membranes
Sample itemA woman at 30 weeks has a gush of clear fluid from the vagina. Speculum examination confirms pooling of liquor. She has no contractions, no fever, and the fetal heart rate is normal. What is the most appropriate management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Admit, give antenatal corticosteroids and antibiotics such as erythromycin, and monitor for chorioamnionitis with expectant management
In preterm prelabour rupture of membranes without infection or fetal compromise, expectant management lowers the risks of prematurity. Antenatal corticosteroids improve neonatal lung maturity, and antibiotics (erythromycin, with amoxicillin in some regimens) prolong latency and reduce infection. Digital examination is avoided because it increases infection risk, and the woman is monitored for chorioamnionitis (fever, maternal tachycardia, uterine tenderness, foul liquor). Delivery is considered from about 34 weeks, earlier if infection or fetal compromise develops.
Option by option
A. Tocolysis with nifedipine for several weeks
Prolonged tocolysis is not recommended after membrane rupture.
B. Immediate induction of labour with oxytocin
Immediate induction at 30 weeks would add the risks of extreme prematurity without a need.
C. Digital vaginal examination to assess the cervix, then discharge
Digital examination raises infection risk and discharge is unsafe.
D. Admit, give antenatal corticosteroids and antibiotics such as erythromycin, and monitor for chorioamnionitis with expectant management (correct)
Correct. Corticosteroids, antibiotics and close monitoring balance maturity against the risk of infection.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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