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Orthopaedics · Bone tumours: benign
Sample itemA 15-year-old boy has a hard, painless bony swelling near the knee that grows with him. X-ray shows a pedunculated bony outgrowth from the metaphysis directed away from the joint, continuous with the marrow cavity. What is the diagnosis, and which feature in adulthood suggests malignant change?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Osteochondroma; growth after skeletal maturity or a thick cartilage cap suggests chondrosarcoma
Osteochondroma is the commonest benign bone tumour, a cartilage-capped outgrowth that points away from the physis and is continuous with the medullary cavity. It stops growing at skeletal maturity. New growth in adulthood, pain, or a cartilage cap thicker than about 2 cm should raise suspicion of secondary chondrosarcoma, which is more likely in multiple hereditary exostoses.
Option by option
A. Ewing sarcoma; onion-skin periosteal reaction
Ewing sarcoma is a destructive lesion with an onion-skin reaction.
B. Giant cell tumour; pain on weight bearing
Giant cell tumour is epiphyseal in adults after growth plate closure.
C. Osteochondroma; growth after skeletal maturity or a thick cartilage cap suggests chondrosarcoma (correct)
Correct. The imaging features are typical, and renewed growth in an adult suggests malignant change.
D. Osteoid osteoma; relief with aspirin
Osteoid osteoma is a small nidus with night pain relieved by NSAIDs, not a pedunculated outgrowth.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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