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Pediatrics · Haematology: ITP
Sample itemA 4-year-old well child has widespread petechiae and bruising for 3 days after a viral illness. Haemoglobin and white cell count are normal, the platelet count is 18 × 10^9/L, and there is no mucosal bleeding or organomegaly. What is the usual management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Observation with advice to avoid trauma, as most resolve spontaneously
Immune thrombocytopenia of childhood is usually self-limiting after a viral infection. If there is no significant bleeding, observation is acceptable even with low counts, with advice on avoiding trauma and contact sports. IVIG, short-course steroids or anti-D are used if there is significant mucosal bleeding. A marrow is only needed if the picture is atypical.
Option by option
A. Immediate splenectomy
Splenectomy is reserved for chronic, refractory cases after many months.
B. Observation with advice to avoid trauma, as most resolve spontaneously (correct)
Correct. Children without significant bleeding can be observed.
C. Platelet transfusion
Transfusion is for life-threatening bleeding, since the platelets are rapidly destroyed.
D. Chemotherapy
Chemotherapy is not indicated for ITP.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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