Gynaecological endocrinology: Turner syndrome and pregnancy: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological endocrinology: Turner syndrome and pregnancy

Sample item

A 28-year-old woman with Turner syndrome (45,X) plans pregnancy using a donated oocyte. Which pre-conception evaluation is most important?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Cardiac imaging for aortic root dilatation and bicuspid aortic valve

Women with Turner syndrome have a risk of aortic dissection that is greatly increased in pregnancy, particularly with a bicuspid valve or an enlarged aortic root. Cardiac MRI or echocardiography and specialist counselling are needed before conception, and some are advised against pregnancy.

Option by option

  • A. Cardiac imaging for aortic root dilatation and bicuspid aortic valve (correct)

    Correct. Aortic dissection is the life-threatening risk that determines whether pregnancy is safe.

  • B. Fasting lipid profile

    Dyslipidaemia may coexist but does not carry the immediate maternal risk.

  • C. Bone density scan

    Osteoporosis is relevant to oestrogen replacement but does not decide safety of pregnancy.

  • D. Thyroid antibody testing

    Thyroid autoimmunity should be checked but is not the greatest threat to maternal life.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Cardiac imaging for aortic root dilatation and bicuspid aortic valve. Women with Turner syndrome have a risk of aortic dissection that is greatly increased in pregnancy, particularly with a bicuspid valve or an enlarged aortic root.

Why is "Fasting lipid profile" not the answer?

Dyslipidaemia may coexist but does not carry the immediate maternal risk.

Why is "Bone density scan" not the answer?

Osteoporosis is relevant to oestrogen replacement but does not decide safety of pregnancy.

Why is "Thyroid antibody testing" not the answer?

Thyroid autoimmunity should be checked but is not the greatest threat to maternal life.

What concept does this question test?

It tests Gynaecological endocrinology: Turner syndrome and pregnancy in OBG. Cardiac MRI or echocardiography and specialist counselling are needed before conception, and some are advised against pregnancy.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological endocrinology: Turner syndrome and pregnancy?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.