Gynaecological oncology: Brenner tumour: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological oncology: Brenner tumour

Sample item

A 60-year-old woman has a solid unilateral ovarian mass that looks like a fibroma. Histology shows nests of urothelium-like epithelium set in dense fibrous stroma. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Brenner tumour

A Brenner tumour is a surface epithelial-stromal tumour made of transitional (urothelial-type) epithelial nests in fibrous stroma. Most are benign and found incidentally in postmenopausal women. They are thought to arise from Walthard cell nests.

Option by option

  • A. Mucinous cystadenoma

    Mucinous cystadenoma is cystic with tall mucin-secreting columnar epithelium.

  • B. Granulosa cell tumour

    Granulosa cell tumours show Call-Exner bodies and oestrogenic effects.

  • C. Thecoma

    A thecoma is made of lipid-rich spindle cells and is oestrogenic.

  • D. Brenner tumour (correct)

    Correct. Urothelium-like nests in a fibrous stroma define it.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is D, Brenner tumour. A Brenner tumour is a surface epithelial-stromal tumour made of transitional (urothelial-type) epithelial nests in fibrous stroma.

Why is "Mucinous cystadenoma" not the answer?

Mucinous cystadenoma is cystic with tall mucin-secreting columnar epithelium.

Why is "Granulosa cell tumour" not the answer?

Granulosa cell tumours show Call-Exner bodies and oestrogenic effects.

Why is "Thecoma" not the answer?

A thecoma is made of lipid-rich spindle cells and is oestrogenic.

What concept does this question test?

It tests Gynaecological oncology: Brenner tumour in OBG. Most are benign and found incidentally in postmenopausal women. They are thought to arise from Walthard cell nests.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological oncology: Brenner tumour?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.