Retina: polypoidal choroidal vasculopathy: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Retina: polypoidal choroidal vasculopathy

Sample item

A 62-year-old Asian man has recurrent serous and haemorrhagic pigment epithelial detachments with orange-red subretinal nodules near the optic disc, only partly responsive to anti-VEGF injections. Which investigation best shows the abnormal vascular network?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Indocyanine green angiography

Polypoidal choroidal vasculopathy is an abnormal branching choroidal network ending in polyp-like dilatations. Indocyanine green angiography images the choroidal circulation and shows the polyps well, and photodynamic therapy with anti-VEGF may be used.

Option by option

  • A. Visual evoked potential

    Visual evoked potential tests the visual pathway and does not image vessels.

  • B. Fundus autofluorescence

    Autofluorescence shows RPE health but not the choroidal vascular channels.

  • C. Indocyanine green angiography (correct)

    Correct. ICG angiography images the choroid and demonstrates the polyps.

  • D. B-scan ultrasonography

    B-scan shows gross structure and has poor resolution for the polypoidal lesions.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Indocyanine green angiography. Polypoidal choroidal vasculopathy is an abnormal branching choroidal network ending in polyp-like dilatations.

Why is "Visual evoked potential" not the answer?

Visual evoked potential tests the visual pathway and does not image vessels.

Why is "Fundus autofluorescence" not the answer?

Autofluorescence shows RPE health but not the choroidal vascular channels.

Why is "B-scan ultrasonography" not the answer?

B-scan shows gross structure and has poor resolution for the polypoidal lesions.

What concept does this question test?

It tests Retina: polypoidal choroidal vasculopathy in Ophthalmology. Indocyanine green angiography images the choroidal circulation and shows the polyps well, and photodynamic therapy with anti-VEGF may be used.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Retina: polypoidal choroidal vasculopathy?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.