Retina: Oguchi disease: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Retina: Oguchi disease

Sample item

A boy has lifelong non-progressive night blindness. His fundus has a golden-yellow sheen that returns to a normal colour after several hours in the dark and reappears after light exposure. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Oguchi disease

Oguchi disease is a recessive form of congenital stationary night blindness in which the fundus colour normalises after prolonged dark adaptation, the Mizuo-Nakamura phenomenon. Vision and fields are otherwise preserved and the condition does not progress.

Option by option

  • A. Retinitis pigmentosa

    Retinitis pigmentosa is progressive with bone-spicule pigment and field loss.

  • B. Oguchi disease (correct)

    Correct. A golden sheen that normalises in the dark is the hallmark of Oguchi disease.

  • C. Vitamin A deficiency

    Vitamin A deficiency causes night blindness with xerosis and Bitot spots, and is not lifelong from birth.

  • D. Fundus albipunctatus

    Fundus albipunctatus shows numerous small white dots at the level of the RPE without a colour change that reverses.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, Oguchi disease. Oguchi disease is a recessive form of congenital stationary night blindness in which the fundus colour normalises after prolonged dark adaptation, the Mizuo-Nakamura phenomenon.

Why is "Retinitis pigmentosa" not the answer?

Retinitis pigmentosa is progressive with bone-spicule pigment and field loss.

Why is "Vitamin A deficiency" not the answer?

Vitamin A deficiency causes night blindness with xerosis and Bitot spots, and is not lifelong from birth.

Why is "Fundus albipunctatus" not the answer?

Fundus albipunctatus shows numerous small white dots at the level of the RPE without a colour change that reverses.

What concept does this question test?

It tests Retina: Oguchi disease in Ophthalmology. Vision and fields are otherwise preserved and the condition does not progress.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Retina: Oguchi disease?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.