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Orthopaedics · Bone tumours: periosteal osteosarcoma
Sample itemA 17-year-old has a painful swelling over the tibial diaphysis. Radiographs show a sunburst reaction arising from the cortical surface, with a cartilaginous matrix on biopsy, and the medullary canal is spared. Which variant of osteosarcoma is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Periosteal osteosarcoma
Periosteal osteosarcoma is a surface tumour of intermediate grade that arises on the diaphysis of a long bone such as the tibia or femur, and is usually chondroblastic. Parosteal osteosarcoma is low grade and typically sits on the posterior distal femur. Surface variants often spare the medullary cavity and have a better prognosis than conventional disease.
Option by option
A. Telangiectatic osteosarcoma
Telangiectatic osteosarcoma is an intramedullary tumour with blood-filled cystic spaces and lytic destruction.
B. Parosteal osteosarcoma
Parosteal osteosarcoma is a low-grade, densely ossified lesion typically on the posterior distal femur.
C. Conventional intramedullary osteosarcoma
The conventional type arises inside the metaphyseal medullary cavity and destroys the cortex from within.
D. Periosteal osteosarcoma (correct)
Correct. A diaphyseal surface tumour with a chondroblastic matrix and a spared canal is periosteal osteosarcoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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