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Orthopaedics · Fractures and dislocations: haemochromatosis arthropathy
Sample itemA 52-year-old man with bronzed skin, diabetes and hepatomegaly has pain and stiffness in his hands. Radiographs show hook-like osteophytes and cystic change. Which joints are characteristically affected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Second and third metacarpophalangeal joints
Haemochromatosis arthropathy classically involves the second and third MCP joints, with hook-like osteophytes on the radial side of the metacarpal heads and chondrocalcinosis. It is a degenerative arthropathy that is not reversed by venesection. Rheumatoid arthritis and nodal osteoarthritis spare this pattern.
Option by option
A. Distal interphalangeal joints
DIP involvement with Heberden nodes is the pattern of nodal osteoarthritis.
B. Second and third metacarpophalangeal joints (correct)
Correct. The second and third MCP joints with hook osteophytes are typical.
C. First carpometacarpal joint alone
The first carpometacarpal joint is the usual site of thumb-base osteoarthritis.
D. Wrist and proximal interphalangeal joints symmetrically
Symmetrical wrist and PIP involvement is the pattern of rheumatoid arthritis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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