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Psychiatry · Psychotic disorders: smooth pursuit eye movements
Sample itemA research team studies oculomotor tasks as a possible endophenotype of schizophrenia. Patients and some of their unaffected first-degree relatives are asked to follow a slowly moving target with their eyes. Which finding is typically reported?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Impaired smooth pursuit with catch-up saccades
Abnormal smooth pursuit eye tracking is found in a large proportion of patients with schizophrenia and in some unaffected relatives, so it is considered a trait marker. It is not specific to schizophrenia, but it supports a genetic contribution to the disorder.
Option by option
A. Internuclear ophthalmoplegia
Internuclear ophthalmoplegia is a brainstem lesion of the medial longitudinal fasciculus, as seen in multiple sclerosis.
B. Impaired smooth pursuit with catch-up saccades (correct)
Correct. Disrupted tracking with intrusive saccades is the replicated finding.
C. Nystagmus on lateral gaze
Gaze-evoked nystagmus suggests a cerebellar or brainstem lesion and is not the described marker.
D. Complete loss of voluntary gaze
Voluntary gaze is not lost; the abnormality lies in tracking a moving target.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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