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Anatomy · Neuroanatomy: Chiari II malformation
Sample itemA newborn with a lumbosacral myelomeningocele develops progressive hydrocephalus. Which finding on MRI is characteristic of the associated hindbrain malformation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Vermis and medulla displaced below the foramen magnum
The Chiari II malformation includes a small posterior fossa with caudal displacement of the cerebellar vermis, medulla and fourth ventricle through the foramen magnum. It is closely linked to open neural tube defects and causes hydrocephalus by obstructing CSF outflow.
Option by option
A. Absent vermis with a large cystic fourth ventricle
Vermis agenesis with a cystic fourth ventricle describes Dandy-Walker malformation.
B. Vermis and medulla displaced below the foramen magnum (correct)
Correct. Caudal herniation of the vermis and medulla through the foramen magnum defines this malformation.
C. Single midline ventricle with fused thalami
A single ventricle with fused thalami is the alobar form of holoprosencephaly.
D. Absent corpus callosum with dilated occipital horns
Absent corpus callosum with colpocephaly is a separate midline malformation not tied to a myelomeningocele.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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