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Anatomy · Neuroanatomy: tonsillar herniation
Sample itemA patient with a large cerebellar tumour and raised intracranial pressure collapses minutes after a lumbar puncture, with irregular breathing progressing to apnoea and bradycardia. Which event best explains the collapse?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Tonsillar herniation compressing the medulla
Lowering lumbar CSF pressure in the presence of a posterior fossa mass can push the cerebellar tonsils into the foramen magnum. This compresses the medulla and its respiratory and cardiovascular centres, causing apnoea and bradycardia.
Option by option
A. Uncal herniation through the tentorial notch
Uncal herniation compresses the oculomotor nerve and midbrain, causing a dilated pupil and hemiparesis before respiratory failure.
B. Subfalcine herniation of the cingulate gyrus
Subfalcine herniation compresses the anterior cerebral artery and causes leg weakness, not apnoea.
C. Tonsillar herniation compressing the medulla (correct)
Correct. The tonsils wedge into the foramen magnum and squeeze the medullary cardiorespiratory centres.
D. Upward herniation of the cerebellar vermis
Upward vermis herniation compresses the midbrain and is a less likely result of lumbar CSF removal.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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