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Anatomy · Embryology: aortic arch anomalies
Sample itemA 40-year-old woman has mild dysphagia. Barium swallow shows an oblique posterior indentation of the oesophagus, and angiography shows the right subclavian artery arising from the descending aorta and passing behind the oesophagus. Which embryological event explains this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Loss of right fourth arch and proximal right dorsal aorta
In an aberrant right subclavian artery, the right fourth arch and the right dorsal aorta above the seventh intersegmental artery disappear. The right subclavian then forms from the distal right dorsal aorta and seventh intersegmental artery and arises from the left side, crossing behind the oesophagus.
Option by option
A. Failed involution of the left dorsal aorta
Failed involution of the left dorsal aorta would not displace the right subclavian origin.
B. Abnormal division of the truncus arteriosus
Truncus arteriosus division defects cause outflow tract anomalies such as transposition.
C. Loss of right fourth arch and proximal right dorsal aorta (correct)
Correct. Loss of the right fourth arch and proximal dorsal aorta moves the origin of the right subclavian artery to the descending aorta.
D. Persistent double aortic arch from both fourth arches
A double aortic arch forms a vascular ring but both subclavian arteries arise normally from their own arches.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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