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General Surgery · Hepatobiliary and pancreatic surgery: location of gastrinoma
Sample itemA patient with recurrent ulcers and a confirmed gastrinoma needs imaging. In which location are most sporadic gastrinomas found?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Duodenal wall within the gastrinoma triangle
Most gastrinomas lie in the gastrinoma (Passaro) triangle bounded by the junction of the cystic and common bile ducts, the second and third parts of the duodenum, and the neck and body of the pancreas. The duodenum is the most frequent site, and the tumours are often small.
Option by option
A. Duodenal wall within the gastrinoma triangle (correct)
Correct. Most arise in the duodenal wall within the triangle.
B. Gastric antrum
The antrum contains G cells, but gastrinomas do not typically arise there.
C. Tail of the pancreas
The pancreatic tail is a less common site than the head and duodenum.
D. Jejunal mesentery
The jejunal mesentery is not a typical primary site.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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