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Microbiology · Bacteriology: Kingella kingae in children
Sample itemA 15-month-old fully immunised child has a limp and a warm swollen knee with low-grade fever and a mildly raised CRP. Synovial fluid culture on routine agar is sterile at 48 hours, but fluid inoculated into a blood culture bottle grows beta-haemolytic Gram-negative coccobacilli in pairs. Which organism is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Kingella kingae
Kingella kingae is a fastidious member of the oropharyngeal flora that causes osteoarticular infection in children under 4 years. Inoculating joint fluid into blood culture bottles greatly improves recovery, and the infection is often milder than that caused by Staphylococcus aureus.
Option by option
A. Streptococcus pyogenes
Streptococcus pyogenes is a Gram-positive coccus in chains and also grows on routine media.
B. Haemophilus influenzae type b
Haemophilus influenzae type b is much less likely in a fully immunised child and needs X and V factors.
C. Kingella kingae (correct)
Correct. A fastidious Gram-negative coccobacillus recovered only in blood culture bottles points to Kingella.
D. Staphylococcus aureus
Staphylococcus aureus is a Gram-positive coccus that grows readily on routine agar.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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