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OBG · Normal pregnancy and antenatal care: cordocentesis
Sample itemA fetus at 24 weeks with suspected severe anaemia needs a direct blood sample for haemoglobin and for an intrauterine transfusion. Which procedure provides access to fetal blood?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Cordocentesis
Percutaneous umbilical blood sampling (cordocentesis) is done under ultrasound guidance after 18 weeks, usually at the placental cord insertion. It gives fetal blood for counts, karyotype and infection tests, and allows intrauterine transfusion.
Option by option
A. Cordocentesis (correct)
Correct. Cordocentesis samples fetal blood from the umbilical vein and permits transfusion.
B. Chorionic villus sampling
Chorionic villus sampling collects placental tissue early in pregnancy and gives no fetal blood.
C. Fetoscopic skin biopsy
Fetal skin biopsy is used for rare genodermatoses and does not give blood.
D. Transabdominal amniocentesis
Amniocentesis yields amniotic fluid containing fetal cells, not blood for transfusion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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