Complications of pregnancy: chlamydia in pregnancy: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Complications of pregnancy: chlamydia in pregnancy

Sample item

A woman at 20 weeks has a positive nucleic acid test for Chlamydia trachomatis from an endocervical swab. Which drug is preferred for treatment?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Azithromycin

Azithromycin as a single dose is the treatment of choice for chlamydia in pregnancy. Tetracyclines such as doxycycline are avoided because they affect fetal bone and teeth, and fluoroquinolones are avoided because of cartilage concerns. A test of cure is advised after treatment.

Option by option

  • A. Ciprofloxacin

    Ciprofloxacin is not recommended in pregnancy because of cartilage toxicity concerns.

  • B. Azithromycin (correct)

    Correct. A single oral dose of azithromycin is safe and effective in pregnancy.

  • C. Doxycycline

    Doxycycline is avoided in pregnancy as it deposits in fetal teeth and bone.

  • D. Levofloxacin

    Levofloxacin shares fluoroquinolone concerns and is not used for chlamydia in pregnancy.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is B, Azithromycin. Azithromycin as a single dose is the treatment of choice for chlamydia in pregnancy.

Why is "Ciprofloxacin" not the answer?

Ciprofloxacin is not recommended in pregnancy because of cartilage toxicity concerns.

Why is "Doxycycline" not the answer?

Doxycycline is avoided in pregnancy as it deposits in fetal teeth and bone.

Why is "Levofloxacin" not the answer?

Levofloxacin shares fluoroquinolone concerns and is not used for chlamydia in pregnancy.

What concept does this question test?

It tests Complications of pregnancy: chlamydia in pregnancy in OBG. Tetracyclines such as doxycycline are avoided because they affect fetal bone and teeth, and fluoroquinolones are avoided because of cartilage concerns. A test of cure is advised after treatment.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Complications of pregnancy: chlamydia in pregnancy?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.