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OBG · Postpartum haemorrhage and emergencies: uterine relaxant in inversion
Sample itemIn acute puerperal uterine inversion, replacement under anaesthesia fails because the cervical ring has tightened around the fundus. Which drug is useful before the next attempt?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Nitroglycerin, to relax the uterus
A uterine relaxant such as nitroglycerin, a beta-agonist or a halogenated anaesthetic gas relaxes the cervical ring so that the fundus can be pushed back. Oxytocin or other uterotonics are given only after replacement to contract the uterus and prevent re-inversion.
Option by option
A. Carboprost, to contract the uterus
Carboprost causes strong contraction and would make replacement harder.
B. Oxytocin infusion, to contract the uterus
Oxytocin is started after replacement, since earlier contraction tightens the ring.
C. Methylergometrine, to contract the uterus
Ergometrine causes tonic contraction and would tighten the ring.
D. Nitroglycerin, to relax the uterus (correct)
Correct. Relaxation of the ring allows replacement of the fundus.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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