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OBG · Postpartum haemorrhage and emergencies: oxytocin bolus effect
Sample itemAt caesarean section the anaesthetist pushes 10 IU of oxytocin as a rapid intravenous bolus. Which haemodynamic effect is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Vasodilatation with hypotension and reflex tachycardia
Oxytocin relaxes vascular smooth muscle when given as a fast bolus, so blood pressure drops and heart rate rises. It is therefore given as a slow infusion or diluted slow injection at caesarean, especially in hypovolaemic or cardiac patients.
Option by option
A. Vasodilatation with hypotension and reflex tachycardia (correct)
Correct. A rapid bolus causes vasodilatation, hypotension and compensatory tachycardia.
B. Bronchospasm with a rise in pulmonary pressure
Bronchospasm is a recognised effect of carboprost, not oxytocin.
C. Hypertension with reflex bradycardia
Hypertension with bradycardia is the pressor response seen with ergometrine.
D. Sustained hypertension with peripheral vasoconstriction
Vasoconstriction with hypertension is the picture of ergot alkaloids, not oxytocin.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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