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OBG · Hypertensive disorders: recurrent seizure on magnesium
Sample itemA woman on maintenance magnesium sulphate for eclampsia has a second convulsion. Reflexes are present and respiration is normal. What is the next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Give a further intravenous bolus of magnesium sulphate
Magnesium sulphate remains the drug of choice. A recurrent fit with preserved reflexes and normal respiration is treated with an additional bolus, while airway and oxygen are secured and the cause is reviewed. Other anticonvulsants are for refractory cases.
Option by option
A. Give calcium gluconate
Calcium gluconate reverses toxicity and would worsen seizure control.
B. Replace magnesium with intravenous phenytoin
Phenytoin is inferior to magnesium and is not a replacement in this setting.
C. Give intravenous diazepam as the primary agent
Diazepam is an alternative only when magnesium is unavailable or has failed.
D. Give a further intravenous bolus of magnesium sulphate (correct)
Correct. An additional bolus raises the level and controls recurrence.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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