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OBG · Gynaecological oncology: malignant transformation in dermoid cyst
Sample itemWhich is the commonest malignancy arising in a mature cystic teratoma of the ovary?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Squamous cell carcinoma
Malignant change in a dermoid cyst is uncommon and usually affects older women. The ectodermal lining gives rise to squamous cell carcinoma in most cases.
Option by option
A. Adenocarcinoma
Adenocarcinoma is a less common transformation.
B. Basal cell carcinoma
Basal cell carcinoma is rare in this setting.
C. Choriocarcinoma
Choriocarcinoma arises from trophoblastic tissue.
D. Squamous cell carcinoma (correct)
Correct. Squamous carcinoma of the ectodermal lining is the commonest.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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