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Ophthalmology · Glaucoma: reversible cupping in infants
Sample itemAfter a successful goniotomy in an infant with raised pressure, the enlarged optic disc cup becomes smaller on follow-up. Why can cupping regress in infants but not in adults?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. The infant scleral canal and lamina cribrosa are elastic and recoil
In young eyes the scleral canal and lamina cribrosa are distensible, so a raised pressure stretches them and a fall in pressure lets them recoil. In adults the tissues are rigid and the cup reflects permanent axonal loss. Regression of cupping is therefore a useful sign of control in infants.
Option by option
A. Infant eyes make less aqueous after surgery
Aqueous production is not the reason the cup changes shape, and it is not reduced by goniotomy.
B. Glial tissue fills the cup in infants
Glial filling would produce permanent pallor, not true regression of the cup.
C. The infant scleral canal and lamina cribrosa are elastic and recoil (correct)
Correct. Elastic tissues stretched by high pressure can recoil, so the cup shrinks in infants.
D. Infant ganglion cells regenerate once pressure falls
Retinal ganglion cells do not regenerate in infants, and the change is mechanical.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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