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Ophthalmology · Glaucoma: cardioselective beta-blocker
Sample itemA glaucoma patient with mild chronic airway disease needs a topical beta-blocker. Which drug has relative beta-1 selectivity and is the usual choice in this situation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Betaxolol
Betaxolol is relatively cardioselective and therefore has less effect on bronchial beta-2 receptors. It lowers pressure slightly less than timolol, and it is still used with caution in patients with airway disease.
Option by option
A. Timolol
Timolol is non-selective and can precipitate bronchospasm.
B. Carteolol
Carteolol is non-selective, with some intrinsic sympathomimetic activity, and does not spare the airways.
C. Levobunolol
Levobunolol is non-selective and carries the same risk of bronchospasm.
D. Betaxolol (correct)
Correct. Betaxolol is relatively beta-1 selective and less likely to provoke bronchospasm.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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