Glaucoma: steroid responders: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: steroid responders

Sample item

Which group is most likely to show a marked rise in intraocular pressure after weeks of topical corticosteroid?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. First-degree relatives of patients with open-angle glaucoma

A strong steroid response is more common in patients with primary open-angle glaucoma and in their first-degree relatives. It also occurs more often in high myopes and diabetics. Pressure should be checked in anyone given prolonged steroid therapy.

Option by option

  • A. Patients with a deep anterior chamber and no disease

    A deep chamber without disease carries no particular predisposition to a steroid response.

  • B. Young hypermetropic patients with narrow angles

    Narrow angles predispose to angle closure, which is a different mechanism from the trabecular response to steroids.

  • C. First-degree relatives of patients with open-angle glaucoma (correct)

    Correct. Relatives of open-angle glaucoma patients are more likely to be high steroid responders.

  • D. Emmetropes without a family history

    Emmetropes without a family history are unlikely to show a marked response.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, First-degree relatives of patients with open-angle glaucoma. A strong steroid response is more common in patients with primary open-angle glaucoma and in their first-degree relatives.

Why is "Patients with a deep anterior chamber and no disease" not the answer?

A deep chamber without disease carries no particular predisposition to a steroid response.

Why is "Young hypermetropic patients with narrow angles" not the answer?

Narrow angles predispose to angle closure, which is a different mechanism from the trabecular response to steroids.

Why is "Emmetropes without a family history" not the answer?

Emmetropes without a family history are unlikely to show a marked response.

What concept does this question test?

It tests Glaucoma: steroid responders in Ophthalmology. It also occurs more often in high myopes and diabetics. Pressure should be checked in anyone given prolonged steroid therapy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: steroid responders?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.