Uvea: pathergy test in Behcet disease: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uvea: pathergy test in Behcet disease

Sample item

A man with recurrent oral aphthae and hypopyon uveitis develops a sterile pustule 24 to 48 hours after a skin needle prick. What is this response called?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Pathergy

Pathergy is a hyperreactive skin response to minor trauma and is a diagnostic feature of Behcet disease. It is more common in patients from the Mediterranean and Asian regions along the Silk Route.

Option by option

  • A. Nikolsky sign

    Nikolsky sign is the shearing off of the epidermis with lateral pressure in pemphigus.

  • B. Pathergy (correct)

    Correct. A sterile pustule at a needle prick site is the pathergy reaction.

  • C. Koebner phenomenon

    The Koebner phenomenon is new lesions of an existing skin disease, such as psoriasis, appearing at sites of trauma.

  • D. Auspitz sign

    Auspitz sign is pinpoint bleeding on scale removal in psoriasis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, Pathergy. Pathergy is a hyperreactive skin response to minor trauma and is a diagnostic feature of Behcet disease.

Why is "Nikolsky sign" not the answer?

Nikolsky sign is the shearing off of the epidermis with lateral pressure in pemphigus.

Why is "Koebner phenomenon" not the answer?

The Koebner phenomenon is new lesions of an existing skin disease, such as psoriasis, appearing at sites of trauma.

Why is "Auspitz sign" not the answer?

Auspitz sign is pinpoint bleeding on scale removal in psoriasis.

What concept does this question test?

It tests Uvea: pathergy test in Behcet disease in Ophthalmology. It is more common in patients from the Mediterranean and Asian regions along the Silk Route.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uvea: pathergy test in Behcet disease?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.